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Summary Hyvärinen et al. [1] carried out a study with the aim of predicting the age of natural menopause (ANM) in middle aged women. They used Cox models with dependent covariates, selecting predictors with lasso regression. For this research, authors analyzed the NAMS longitudinal study "Study of estrogen regulation of muscle apoptosis" consisting of 6,878 women initially… Read More

Summary Vitamin D is essential for optimal musculoskeletal health because it promotes calcium absorption, mineralization of osteoid tissue formation in bones, and the maintenance of muscle function [1]. Vitamin D supplementation has been considered beneficial for the prevention and treatment of osteoporosis. Burt et al. [2], conducted a 3-year, double-blind, randomized clinical trial. The dose-response… Read More

Summary Recently Persson et al. [1] performed a study to assess whether a diagnosis of polycystic ovarian syndrome (PCOS) was associated with an increased risk of type II diabetes (T2D) in later life, taking into consideration whether the PCOS was associated with hyperandrogenism (HA) or not (NA), and also taking account of body mass index… Read More

Summary Postmenopausal women experience different physical and psychological symptoms throughout their lives. One of the disturbing complaints caused by reduced estrogen levels is atrophy of the urogenital tract. Although Menopausal hormone therapy (MHT) is used as an effective treatment to reduce symptoms of urogenital atrophy during menopause, it has controversies related to an increase in… Read More

Summary Recently, Ballot et al. [1] reported the results of a secondary analysis of a 5-year prospective longitudinal population-based survey conducted in Canada, regarding the natural history of insomnia. They analyzed the association between sleep reactivity, arousal predisposition, sleep disturbances, and menopause. For this, 873 women aged 40 to 60 were divided into 2 groups… Read More

Summary Despite the fact that during the perimenopause there is a decline in attention and working/verbal memory, there are significant individual differences. The exact contributions of hormones and menopausal symptoms to domain-specific cognitive functions remain unknown. Bearing this in mind, recently, Weber et al [1] published results of the Rochester Investigation of Cognition Across Menopause… Read More

Summary García-Alfaro et al [1] published the results of a cross-sectional study that aimed at determining the impact of age, age at menopause, body mass index (BMI), and lumbar and hip bone mineral density (BMD) on muscle strength of 392 young postmenopausal women (65 or less years), with no physical disabilities and normal serum 25-hydroxyvitamin… Read More

Summary Vinogradova et al. [1] undertook a nested case-control study using prospectively collected electronic health records from two largest UK primary care databases in order to assess the risk of breast cancer associated with different types and duration of menopausal hormone therapy (MHT). They identified 98,611 women aged 50-79 with a primary diagnosis of breast… Read More

Summary Recently, Ruan et al [1] published results of a study that aimed at investigating the genitourinary syndrome of menopause (GSM) in a large cohort of peri- and postmenopausal Chinese women. They analyzed the dependency on age and menopausal status and possible differences between non-hysterectomized and hysterectomized women. For this they assessed over 2 years,… Read More

Summary Hot flushes and night sweats (vasomotor symptoms, VMS) are one of the most common symptoms of menopause and a leading patient priority for treatment [1]. New therapies are emerging, but comparing the safety and effectiveness of treatments for VMS is limited by the use of different outcome measures between studies. Further, it is uncertain… Read More