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Summary The Kronos Early Estrogen Prevention Study (KEEPS) was a randomized, double-blind, placebo-controlled trial designed to determine the effects of menopausal hormone treatments (MHTs) on the progression of carotid intima-medial thickness (CIMT) in recently menopausal women) [1]. Participants less than 3 years from menopause and without a history of overt cardiovascular disease (CVD), defined as… Read More

Summary Recently, Balcázar-Hernández et al. [1] published the findings of an interesting study that aimed at evaluating the clinical features, severity, and mortality related to COVID-19 among hospitalized mid-aged and older women. Risk factors related to the disease severity and mortality of these women were also analyzed. The study had a retrospective design in hospitalized… Read More

Summary Recently, Rosario et al [1] have published an interesting review on novel approaches aimed at restoring fertility in women with premature ovarian insufficiency (POI) [1]. This entity is characterized by oligo/amenorrhea, high follicle stimulating hormone (FSH) (over 25 IU/L or 40 IU/L), low estradiol (<50 pmol/L) in women younger than 40 years of age.… Read More

Summary The February issue of "Climacteric" brought us various excellent reviews on the "Therapies for menopausal management - current status", with, in our view, a "key statement" from Langer et al. [1] on the use of HRT, important contributions for "compounded bioidentical" products [2], and a review on misunderstandings and misconception of "bioidentical hormones" summarized… Read More

Summary Gabes et al. [1] aimed to assess the structural validity of the Day-to-Day Impact of Vaginal Aging (DIVA) questionnaire, in order to eventually refine the current available version. Postmenopausal women reporting vaginal symptoms related to menopause participated in the study in Germany. Item characteristic curves were analyzed to observe whether the response categories were… Read More

Summary Recently Hashiguchi et al. [1] published a short report aimed at determining the most relevant explanatory variable for female mid-aged health: mindfulness, self-compassion, or acceptance. For this purpose, a total of 200 Japanese women aged 40 to 60 years completed self-reported measures of symptoms (depressive and menopausal), quality of life (physical and mental), and… Read More

Summary In order to elucidate several neuromuscular mechanisms, and investigate cortical inhibition and peripheral muscle twitch force potentiation in women during the perimenopause, Pesonen et al [1] recently studied 63 perimenopausal women (48-55 years) categorized as early (EP, n = 25) or late (LP, n = 38) in accordance to their serum FSH levels and… Read More

Summary Zhu D et al. [1] pooled individual-level data from 23,365 women of six prospective studies which contributed to the InterLACE consortium. Women who experienced cardiovascular disease (CVD) events before baseline were excluded. The associations between frequency (never, rarely, sometimes and often), severity (never, mild, moderate and severe), and timing (before or after age at… Read More

Summary Who would think of such a crazy idea to design a study on possible association between beauty and reproductive longevity? Well, it appears that researchers from Wrocław, Poland did it and now published their interesting findings [1]. The cohort included 211 participants, recruited via social networks, information in local newspapers or on a local… Read More

Summary Recently Syed Alwi et al [1] reported data of 324 mid-aged indigenous women (40-65 years) from Sarawak, a state of Malaysia. They performed a face to face survey in order to explore their perceptions of the menopause. Approximately 30% of surveyed women were pre-, peri- and postmenopausal. A 22.5% agreed that problems occurring during… Read More